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1

Pharmacokinetics of oral diltiazem and five of its metabolites in patients with chronic renal failure

Maha Tawashi, Julien Marc-aurèle, Daniel Bichet, Jean Spénard, Lyne Larivière, Daniel Plante, Gilles Caillé

Journal:

Biopharmaceutics & Drug Disposition

Year:

1991

Language:

english

File:

PDF, 422 KB

english, 1991

2

T1013 A Multicentric, Double-Blind, Randomized Placebo-Controlled Trial of High Dose Ursodeoxycholic Acid in Patients with Non-Alcoholic Steatohepatitis (NASH)

Ratziu, Vlad, De Ledinghen, Victor, Frederic, Oberti, Mathurin, Philippe, Bladou, Claire Wartelle, Renou, Christophe, Spénard, Jean

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 74 KB

english, 2009

3

Comparative pharmacokinetics and pharmacodynamics of two marketed bid formulations of diltiazem in healthy volunteers

Sonia Guimont, Dr Hélène Landriault, Keith Klischer, Michael Grace, Chantal Lambert, Gilles Caillé, Denis Gossard, Anthony Russell, Manon Raymond, Edna Hutchings, Jean Spénard

Journal:

Biopharmaceutics & Drug Disposition

Year:

1993

Language:

english

File:

PDF, 586 KB

english, 1993

4

Efficacy of mesalamine rectal gel in distal ulcerative colitis. A pilot study

Aumais, Guy, Lefebvre, Marc, Massicotte, Julie, Tremblay, Claude, Pierre, Katcha, Cardinal, Cynthia, Spenard, Jean

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 174 KB

english, 2003

5

Combining ursodeoxycholic acid or its NO-releasing derivative NCX-1000 with lipophilic antioxidants better protects mouse hepatocytes against amiodarone toxicity

Ouazzani-Chahdi, Amine, Elimadi, Aziz, Chabli, Allal, Spénard, Jean, Colin, Patrick, Haddad, Pierre S.

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

2007

Language:

english

File:

PDF, 318 KB

english, 2007

6

Bioavailability of metformin in tablet form using a new high pressure liquid chromatography assay method

Gilles Caillé, Yves Lacasse, Manon Raymond, Hélène Landriault, Maria Perrotta, Gianfranca Picirilli, Jean Thiffault, Jean Spénard

Journal:

Biopharmaceutics & Drug Disposition

Year:

1993

Language:

english

File:

PDF, 308 KB

english, 1993

7

Efficacy and safety of mesalamine 1 g HS versus 500 mg BID suppositories in mild to moderate ulcerative proctitis: A multicenter randomized study

Mark Lamet, Theodore Ptak, Chrystian Dallaire, Umed Shah, Michael Grace, Jean Spenard, Danielle de Montigny

Journal:

Inflammatory Bowel Diseases

Year:

2005

Language:

english

File:

PDF, 85 KB

english, 2005

8

Chronic Effects of Diltiazem on the Hemodynamic and Sympathoadrenal Tone in Responsive and Nonresponsive Hypertensive Patients at Rest and During Isometric Exercise

de Champlain, Jacques, Petrovich, Milenko, Lebeau, Réal, Yacine, Amine, Nadeau, Réginald, Spénard, Jean

Journal:

Journal of Cardiovascular Pharmacology

Year:

1991

File:

PDF, 388 KB

1991

9

Pharmacokinetics of intravenous diltiazem and five of its metabolites in patients with chronic renal failure and in healthy volunteers

Maha Tawashi, Julien Marc-aurèle, Daniel Bichet, Jean Spénard, Lyne Larivière, Daniel Plante, Gilles Caillé

Journal:

Biopharmaceutics & Drug Disposition

Year:

1991

Language:

english

File:

PDF, 330 KB

english, 1991

10

Pharmacokinetics of Single Intravenous and Oral Doses of Dolasetron Mesylate in Healthy Elderly Volunteers

Dempsey, Ellen, Bourque, Stéphane, Spénard, Jean, Landriault, Hélène

Journal:

Journal of Clinical Pharmacology

Year:

1996

Language:

english

File:

PDF, 1.24 MB

english, 1996

11

PHARMACOKINETICS AND SAFETY OF SINGLE INTRAVENOUS AND ORAL DOSES OF DOLASETRON MESYLATE IN HEALTHY WOMEN

ANTHER C. F. KEUNG, HÉLÈNE LANDRIAULT, MARC LEFEBVRE, DENIS GOSSARD, ELLEN E. DEMPSEY, MARTIN JUNEAU, DAN DIMMITT, MARK CASTLES, LISA ROBERTS, JEAN SPÉNARD

Journal:

Biopharmaceutics & Drug Disposition

Year:

1997

Language:

english

File:

PDF, 136 KB

english, 1997

12

A comparison of triamcinolone acetonide nasal aerosol spray and fluticasone propionate aqueous solution spray in the treatment of spring allergic rhinitis

Small, Peter, Houle, Pierre-Alain, Day, James H., Briscoe, Maureen, Gold, Milton, Brodarec, Ivan, Pong, Anthony Ham, Mandl, Michael, Spénard, Jean, Phillips, Robert, Furlan, Monique

Journal:

Journal of Allergy and Clinical Immunology

Year:

1997

Language:

english

File:

PDF, 416 KB

english, 1997

13

Bismuth-based quadruple therapy using a single capsule of bismuth biskalcitrate, metronidazole, and tetracycline given with omeprazole versus omeprazole, amoxicillin, and clarithromycin for eradication of helicobacter pylori in duodenal ulcer patients: a prospective, randomized, multicenter, north american trial

Loren Laine, Richard Hunt, Hala El-Zimaity, Bich Nguyen, Michael Osato, Jean Spénard

Journal:

American Journal of Gastroenterology

Year:

2003

Language:

english

File:

PDF, 61 KB

english, 2003

14

Is there a difference in eradication rate of helicobacter pylori between peptic ulcer patients and non-ulcer dyspepsia patients? A survey of 1666 patients

Spenard, Jean, Colin, Patrick, Phanna, Axcan

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 197 KB

english, 2000

15

NCX 1000 Alone or in Combination with Vitamin E Reverses Experimental Nonalcoholic Steatohepatitis in the Rat Similarly to UDCA

Haddad, Yara, Vallerand, Diane, Brault, Antoine, Spénard, Jean, Haddad, Pierre S.

Journal:

International Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 2.21 MB

english, 2011

16

NCX-1000, a Nitric Oxide–Releasing Derivative of UDCA, Does Not Decrease Portal Pressure in Patients With Cirrhosis: Results of a Randomized, Double-Blind, Dose-Escalating Study

Berzigotti, Annalisa, Bellot, Pau, De Gottardi, Andrea, Garcia-Pagan, Juan Carlos, Gagnon, Caroline, Spénard, Jean, Bosch, Jaime

Journal:

American Journal of Gastroenterology

Year:

2010

Language:

english

File:

PDF, 193 KB

english, 2010

17

Influence of Sex, Age and Smoking Status on Patient Comfort during Gastroscopy with Pharyngeal Anesthesia by a New Benzocaine-Tetracaine Preparation

Gelly, André L, Farley, Alain, Boyer, Judy, Asselin, Michelle, Spénard, Jean

Journal:

Canadian journal of gastroenterology

Year:

1998

File:

PDF, 1.49 MB

1998

18

T1047 Efficacy and Safety of Ultrase Mt20® (UMT20) in Improving the Coefficient of Fat Absorption in Children with Cystic Fibrosis and Pancreatic Insufficiency

Konstan, Michael W., Strausbaugh, Steven, Nasr, Samya Z., Graff, Gavin R., Spénard, Jean, Grondin, Josée

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 68 KB

english, 2009

19

S1903 Beneficial Effects of UDCA and Ncx-1000 Alone or in Combination with Vitamin E in a Nonalcoholic Steatohepatitis Rat Model

Haddad, Yara, Vallerand, Diane, Brault, Antoine, Spenard, Jean, Haddad, Pierre S.

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 79 KB

english, 2008

20

Efficacy and safety of mesalamine suppositories for treatment of ulcerative proctitis in children and adolescents

Melvin B. Heyman, Jaroslaw Kierkus, Jean Spénard, Hadia Shbaklo, Monique Giguere

Journal:

Inflammatory Bowel Diseases

Year:

2010

Language:

english

File:

PDF, 148 KB

english, 2010

21

Influence of Omeprazole on Bioavailability of Bismuth following Administration of a Triple Capsule of Bismuth Biskalcitrate, Metronidazole, and Tetracycline

Spénard, Jean, Aumais, Christian, Massicotte, Julie, Tremblay, Claude, Lefebvre, Marc

Journal:

Journal of Clinical Pharmacology

Year:

2004

Language:

english

File:

PDF, 92 KB

english, 2004

22

Efficacy of bismuth-based quadruple therapy for eradication of helicobacter pylori: A survey of 1639 patients

Spenard, Jean, Colin, Patrick, Pharma, Axcan

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 154 KB

english, 2000

23

THE BRISTOL ROYAL INFIRMARY AND THE PLURALITY OF HOSPITAL APPOINTMENTS.

Spenard, Jean, Colin, Patrick, Pharma, Axcan

Journal:

Year:

1907

Language:

english

File:

PDF, 341 KB

english, 1907

24

W1178 Clinical Efficacy and Safety of Mesalamine Suppositories in the Treatment of Pediatric Patients with Ulcerative Proctitis: A Multicenter, Open-Label Study

Heyman, Melvin B., Kierkus, Jaroslaw, Spénard, Jean, Giguere, Monique

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 77 KB

english, 2009

25

Comparative effects of diltiazem sustained-release formulation and metoprolol on ambulatory blood pressure and plasma lipoproteins

Lacourcière, Yves, Poirier, Luc, Boucher, Sylvain, Spenard, Jean

Journal:

Clinical Pharmacology & Therapeutics

Year:

1990

Language:

english

File:

PDF, 518 KB

english, 1990

26

Bismuth-Based Quadruple Therapy Using a Single Capsule of Bismuth Biskalcitrate, Metronidazole, and Tetracycline Given With Omeprazole Versus Omeprazole, Amoxicillin, and Clarithromycin for Eradication of Helicobacter pylori in Duodenal Ulcer Patients: a Prospective, Randomized, Multicenter, North American Trial

Laine, Loren, Hunt, Richard, El-Zimaity, Hala, Nguyen, Bich, Osato, Michael, Spenard, Jean

Journal:

American Journal of Gastroenterology

Year:

2003

Language:

english

File:

PDF, 61 KB

english, 2003

27

Efficacy and Safety of a New Formulation of Pancrelipase (Ultrase MT20) in the Treatment of Malabsorption in Exocrine Pancreatic Insufficiency in Cystic Fibrosis

Konstan, Michael W., Liou, Theodore G., Strausbaugh, Steven D., Ahrens, Richard, Kanga, Jamshed F., Graff, Gavin R., Moffett, Kathryn, Millard, Susan L., Nasr, Samya Z., Siméon, Édith, Spénard, Jean,

Journal:

Gastroenterology Research and Practice

Year:

2010

Language:

english

File:

PDF, 180 KB

english, 2010

28

THE INFLUENCE OF TIME OF ADMINISTRATION ON THE PHARMACOKINETICS OF A ONCE-A-DAY DILTIAZEM FORMULATION: MORNING AGAINST BEDTIME

Jean Thiffault, Hélène Landriault, Denis Gossard, Manon Raymond, Gilles Caillé, Jean Spénard

Journal:

Biopharmaceutics & Drug Disposition

Year:

1996

Language:

english

File:

PDF, 490 KB

english, 1996

29

Effects of food and formulation on the relative bioavailability of bismuth biskalcitrate, metronidazole, and tetracycline given for Helicobacter pylori eradication

Jean Spénard, Christian Aumais, Julie Massicotte, Jean-Sébastien Brunet, Claude Tremblay, Michael Grace, Marc Lefebvre

Journal:

British Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 141 KB

english, 2005

30

A multicenter, partially blinded, randomised study of the efficacy of photodynamic therapy (PDT) using porfimer sodium (POR) for the ablation of high-grade dysplasia (HGD) in Barrett's esophagus (BE): Results of 6-month follow-up

Bergein F. Overholt, Rodger C. Haggitt, Mary P. Bronner, Shari L. Taylor, Yong Hao, Patrick Colin, Jean Spenard, Michelle Depot, Axcan Pharma

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 196 KB

english, 2001

31

Lack of Effect of Sex and Disease State on the Pharmacokinetics of Porfimer Sodium

Jean-Marie Houle, Nadine Clervoix, Stacey Bain, Dr Jean Spénard

Journal:

Clinical Pharmacokinetics

Year:

2006

Language:

english

File:

PDF, 126 KB

english, 2006

32

Rectal tissue, plasma, and urine concentrations of mesalamine (5-ASA) after single and multiple administrations of suppositories to ulcerative proctitis (UP) patients

Aumais, Guy, Bitton, Alain, Martin, Francois, Giard, Alain, Marc, Lefebvre, Tremblay, Claude, Spenard, Jean

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 351 KB

english, 2001

33

Bismuth-Based Triple Therapy with Bismuth Subcitrate, Metronidazole and Tetracycline in the Eradication of Helicobacter pylori : A Randomised, Placebo Controlled, Double-Blind Study

van Zanten, Sander Veldhuyzen, Farley, Alain, Marcon, Norman, Lahaie, Raymond, Archambault, André, Hunt, Richard, Bailey, Robert, Owen, David, Spénard, Jean, Stiglick, Alan, Aimola, Nick, Colin, Patri

Journal:

Canadian journal of gastroenterology

Year:

2000

File:

PDF, 1.19 MB

2000

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